The Denton ISD Division of Academic Programs oversees all educational initiatives of district schools. It is composed of almost every division and department in Denton ISD related to student education.

As part of the division's oversight, its four Area Superintendents, Dr. Jeff Russell, Dr. Charlene Parham, Robin Brownell and Luci Schulz provide guidance to school principals and department heads who oversee educational and student-related endeavors within the four high school learning zones. In addition to oversight, the division supervises and evaluates all elementary and secondary principals, playing a key role in the leadership at the campus level.